Command Headquarters

10311 Wilson Boulevard, Bldg D-2
Post Office Box 1993 
Blythewood, SC 29016
Office: 803-896-5500
Fax: 803-896-5526

Region 1 Office - Columbia

(Calhoun, Clarendon, Kershaw, Lee, Lexington, Orangeburg, Richland and Sumter counties)

1239 Columbia Avenue 
Irmo, SC 29063
Office: 803-935-5740
Fax: 843-935-5741

Region 2 Office - Greenwood

(Abbeville, Aiken, Edgefield, Greenwood, Laurens, McCormick, Newberry, and Saluda counties)

1802 Bypass 25 SE 
Greenwood, SC 29646

Region 3 Office - Greenville

(Anderson, Greenville, Oconee, Pickens, and Spartanburg counties)

33 Villa Road, Suite 200 
Post Office Box 124
Greenville, SC 29615-3037

Region 4 Office - Rock Hill

(Cherokee, Chester, Chesterfield, Fairfield, Lancaster, Union, and York counties)

Rock Hill Business Technology Center
454 S. Anderson Road, Suite 400 
Rock Hill, SC 29730

Region 5 Office - Florence

(Darlington, Dillon, Florence, Georgetown, Horry, Marion, Marlboro, and Williamsburg counties)

3415 East Palmetto Street
Florence, SC 29503

Region 6 Office - Charleston

(Allendale, Bamberg, Barnwell, Beaufort, Berkeley, Charleston, Colleton, Dorchester, Hampton, and Jasper counties)

Dorchester Weigh Station
Interstate 26 West, Mile Marker 174
Post Office Box 669
St. George, SC 29479

Special Operations

Post Office Box 1993
Blythewood, SC  29016
Office: (803) 896-5500 

Fuel Dye

Post Office Box 1993
Blythewood, SC  29016
Office: (803) 896-5500

Motor Carrier Compliance Unit

Post Office Box 1993
Blythewood, SC  29016
Office: (803) 896-5500